Active Ingredient: Glyceryl trinitrate
For this indication, competent medicine agencies globally authorize below treatments:
Rectal
3 mg
1.5 mg 2 time(s) per day every day
A finger covering, such as cling film or a finger cot, may be placed on the finger to be used to apply the ointment. (Finger cots to be obtained separately from local pharmacy or surgical supplies retailer or cling film from local store). The finger is placed along side a 2.5cm dosing line which is provided on the outside carton in which glyceryl trinitrate is supplied, and a strip of ointment the length of the line is expressed onto the end of the finger by gently squeezing the tube. The amount of ointment expressed is approximately 375 mg (1.5 mg GTN). The covered finger is then gently inserted into the anal canal to the distal interphalangeal joint of the finger and applied circumferentially to the anal canal.
The dose delivered from the 4 mg/g ointment is 1.5 mg glyceryl trinitrate. The dose is to be applied intra-anally every twelve hours. Treatment may be continued until the pain abates, up to a maximum of 8 weeks.
Glyceryl trinitrate should be used following conservative treatment failure for acute symptoms of anal fissure.
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