GLYCERYL TRINITATE Sublingual tablets Ref.[7277] Active ingredients: Glyceryl trinitrate

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2017  Publisher: Macarthys Laboratories Ltd T/A Martindale Pharma, Bampton Road, Harold Hill, Romford, RM3 8UG

Product name and form

GTN 300mcg.

Glyceryl Trinitrate 300 micrograms Tablets.

Pharmaceutical Form

Sublingual tablet.

Plain White biconvex tablets 0.5mm diameter.

Qualitative and quantitative composition

Each tablet contains 300 micrograms Glyceryl Trinitrate equivalent to 0.3mg glyceryl trinitrate.

Excipients with known effect:

Contains lactose: 2.880mg.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Glyceryl trinitrate

Glyceryl trinitrate is a vasodilator and is used for angina of effort. Vasodilation is achieved by the releasing of free redical nitric oxide which activates guanylate cyclase and increases synthesis of guanosine 3′ and 5′-monophosphate with resultant effects on the phosphorylation of proteins in smooth muscle. If taken in excess, its vasodilatory effect can cause headache.

List of Excipients

Mannitol
Acacia
Lactose
Talc
Stearic acid
Magnesium stearate

Pack sizes and marketing

Amber glass bottle with aluminium wadded cap packed in a cardboard carton along with a patient leaflet.

Pack size: 100 tablets.

Marketing authorization holder

Macarthys Laboratories Ltd T/A Martindale Pharma, Bampton Road, Harold Hill, Romford, RM3 8UG

Marketing authorization dates and numbers

PL 01883/5958R

Date of first authorization: 20th June 1990

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