Revision Year: 2018
For the treatment of the following infections caused by susceptible microorganisms:
As step down treatment for infections due to susceptible organisms, initially given antimicrobial therapy, particularly parenteral ampicillin-sulbactam.
Usual Dose in Adults and Children weighing ≥30 kg who can swallow tablet whole: 750 mg twice daily.
Usual Duration of Treatment: 5 to 14 days which may be extended depending
on the type and severity of infection.
Non-complicated gonococcal infection: 2.25 g (three 750 mg tablets) as a
single dose.
after the patient becomes asymptomatic or evidence of bacterial eradication has been obtained.
therapy should be continued for at least 10 days to help prevent the occurrence of acute rheumatic fever or glomerulonephritis.
field examinations before receiving sultamicillin and monthly serological tests for a minimum of four months.
Or, as prescribed by a physician.
Ampicillin + sulbactam overdose may manifest as extensions of the drugs’ adverse effects. It should be considered that high CSF concentrations of beta-lactam antibiotics may cause neurologic effects including seizures.
Since ampicillin and sulbactam are removed by hemodialysis, this procedure should be considered during overdosage in patients with renal impairment. For overdosage in patients with normal renal function, hemodialysis may not be necessary and only appropriate measures should be taken.
Store at temperatures not exceeding 25°C.
Keep the product out of sight and reach of children.
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