AKILEN Film-coated tablet Ref.[28110] Active ingredients: Verapamil

Source: Υπουργείο Υγείας (CY)  Revision Year: 2019  Publisher: Medochemie Ltd, 1-10 Constantinoupoleos street, 3011 Limassol, Cyprus

Product name and form

Akilen 40 mg film-coated tablets.

Pharmaceutical Form

Film-coated tablet.

Very pale green, round, convex film-coated tablets, with diameter of core 7 mm.

Qualitative and quantitative composition

Film coated tablets containing 40mg of verapamil hydrochloride.

Excipients with known effect:

Lactose. Each 40 mg film-coated tablet contains 40mg lactose monohydrate.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Verapamil

Verapamil inhibits the transmembrane influx of calcium ions into the heart and vascular smooth muscle cell. The myocardial oxygen demand is lowered directly as a result of the effect on the energy consuming metabolic processes of the myocardial cell and indirectly due to a reduction of the afterload. Due to its effect on coronary vascular smooth muscle, verapamil enhances myocardial blood flow, even in post‐stenotic areas, and relieves coronary spasms. These properties contribute to the anti‐ischaemic and antianginal efficacy of verapamil in all types of coronary artery disease.

List of Excipients

Lactose monohydrate
Croscarmellose sodium
Cellulose microcrystalline
Silica colloidal anhydrous
Magnesium stearate
Polyethylene glycol 6000
Opadry green OY-3875H (Hypromellose (E464), titanium dioxide (E171), macrogol/polyethylene glycol 400, indigo carmine aluminium lake (E132), iron oxide yellow (E172), iron oxide black (E172))

Pack sizes and marketing

Combination polyvinylchloride film and aluminium foil blisters of ten tablets.

Blisters are placed, with a patient information leaflet, in a card carton. Packs of 50, 100, 250, 500 and 1000 tablets are available.

Not all pack sizes may be marketed.

Marketing authorization holder

Medochemie Ltd, 1-10 Constantinoupoleos street, 3011 Limassol, Cyprus

Marketing authorization dates and numbers

MA032/03801

28.12.2006 / 05.07.2012

Drugs

Drug Countries
AKILEN Cyprus, Hong Kong, Malta

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