CLIMEN Tablet Ref.[50748] Active ingredients: Cyproterone Estradiol

Source: Web Search  Revision Year: 2009  Publisher: Bayer Pharma AG Germany.

Product name and form

Climen, coated tablet.

Pharmaceutical Form

Coated tablet.

This medication contains a combination of an oestrogen and a progestin (micronised cyproterone acetate).

This medication is indicated for the treatment of disorders resulting from oestrogen deficiency associated with menopause. It is prescribed as a hormone replacement therapy (HRT).

Qualitative and quantitative composition

The active substances are:

Micronised estradiol valerate: 2.000 mg

Contained in each white coated tablet.

Micronised estradiol valerate: 2.000 mg
Micronised cyproterone acetate: 1.000 mg

Contained in each pink coated tablet.

Active Ingredient Description
Cyproterone

Cyproterone acetate acts as an antiandrogen by blocking androgen receptors. It also has progestogenic activity, which exerts a negative feedback effect on hypothalamic receptors, so leading to a reduction in gonadotrophin release, and hence to diminished production of testicular androgens. Sexual drive and potency are reduced and gonadal function is inhibited.

Estradiol

Estradiol, is chemically and biologically identical to endogenous human estradiol. It substitutes for the loss of oestrogen production in menopausal women, and alleviates menopausal symptoms. Oestrogens prevent bone loss following menopause or ovariectomy.

List of Excipients

Lactose, corn starch, povidone, talc, magnesium stearate, sucrose, macrogol 6000, calcium carbonate, wax E, glycerol, titanium dioxide, iron oxide yellow, iron oxide red pigment.

Pack sizes and marketing

This medication is available as a coated tablet. Each box contains 21 tablets.

Marketing authorization holder

Bayer Pharma AG – Germany.

Drugs

Drug Countries
CLIMEN Austria, Estonia, Spain, Malta, Turkey, South Africa

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