Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2018 Publisher: Galderma (UK) Limited, Meridien House, 69-71 Clarendon Road, Watford, Herts., WD17 1DS, UK
Differin 0.1% w/w Cream.
| Pharmaceutical Form |
|---|
|
Cream. White shiny cream. |
Adapalene 0.1% w/w.
1g cream contains 1mg adapalene.
Excipients with known effect:
Methyl parahydroxybenzoate (E218)
Propyl parahydroxybenzoate (E216)
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Adapalene |
Adapalene is a retinoid-like compound which in, in vivo and in vitro models of inflammation, has been demonstrated to possess anti-inflammatory properties. Mechanically, adapalene binds like tretinoin to specific retinoic acid nuclear receptors but, unlike tretinoin not to cytosolic receptor binding proteins. Adapalene is used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. |
| List of Excipients |
|---|
|
Carbomer 934P |
Collapsible Aluminium tube coated internally with an epoxy-phenolic resin and fitted with a white Polypropylene screw cap. Pack sizes 5g (Sample Pack), 30g, 45g and 50g.
Not all pack sizes may be marketed.
Galderma (UK) Limited, Meridien House, 69-71 Clarendon Road, Watford, Herts., WD17 1DS, UK
PL 10590/0029
9 January 1998
| Drug | Countries | |
|---|---|---|
| DIFFERIN | Austria, Brazil, Canada, Ecuador, Estonia, Finland, Hong Kong, Ireland, Japan, Lithuania, Netherlands, New Zealand, Poland, Singapore, Turkey, United Kingdom, United States, South Africa |
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