LANACANE Creme Ref.[8442] Active ingredients: Benzocaine

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2021  Publisher: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 4AQ

Pharmacodynamic properties

Pharmacotherapeutic group: Antipruritics, incl. Antihistamines, Anesthetics, etc
ATC Code: D04AB04

Benzocaine applied to the skin acts as a topical local anaesthetic, acting on nerve endings and receptors, temporarily reducing the itching and minor pain associated with various thermal, mechanical or chemical stimuli. The vanishing creme base also helps soothe, lubricate, and protect irritated skin.

Pharmacokinetic properties

When used as directed, some benzocaine applied topically may be absorbed through the skin and mucous membranes and is hydrolysed by esterases in the plasma and in the liver, but this should be of negligible consequence. Benzocaine has the quickest onset and shortest duration of action of the commonly used topical anaesthetics.

Preclinical safety data

None.

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