MEDOVIR Cream Ref.[28215] Active ingredients: Aciclovir

Source: Υπουργείο Υγείας (CY)  Revision Year: 2019  Publisher: MEDOCHEMIE LTD, 1-10 Constantinoupoleos street, 3011 Limassol, Cyprus

4.1. Therapeutic indications

Medovir cream is indicated for the treatment of Herpes Simplex virus infections of the skin including initial and recurrent genital herpes and herpes labialis.

4.2. Posology and method of administration

Posology

Adults and children

Medovir cream should be applied five times daily, at approximately four hourly intervals, omitting the night time application.

Medovir Cream should be applied to the lesions or impending lesions as soon as possible, preferably during the early stages (prodrome or erythema). Treatment can also be started during the later (papule or blister) stages.

Treatment should be continued for at least 4 days for herpes labialis and for 5 days for genital herpes. If healing has not occurred then treatment may be continued for up to an additional 5 days.

Elderly

No special comment.

Method of administration

Topical. Do not use in eyes.

Wash hands before and after administration. Always replace the cap on the tube securely.

4.9. Overdose

No untoward effects would be expected if the entire contents of a 10-gram tube of aciclovir cream containing 500 mg of aciclovir were ingested orally. However, the accidental, repeated overdose of oral aciclovir, over several days has resulted in gastrointestinal effects (nausea and vomiting) and neurological effects (headache and confusion).

Aciclovir is dialysable by haemodialysis.

6.3. Shelf life

3 years.

6.4. Special precautions for storage

Store below 25°C, in the original package, in order to protect from light and moisture.

6.5. Nature and contents of container

Aluminium flexible tubes with a plastic screw cap in a carton with the patient information leaflet. Tubes of 5g and 10 g are available.

Not all pack sizes may be marketed.

6.6. Special precautions for disposal and other handling

Any unused product or waste material should be disposed of in accordance with local requirements.

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