MURIPOCIN 2% w/w Ointment Ref.[7728] Active ingredients: Mupirocin

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2018  Publisher: Focus Pharmaceuticals Ltd, Capital House, 85 King William Street, London EC4N 7BL, United Kingdom

Therapeutic indications

Mupirocin is indicated in adults and children.

Mupirocin is a topical antibacterial agent, active against those organisms responsible for the majority of skin infections, e.g. Staphylococcus aureus, including methicillin-resistant strains, other staphylococci, streptococci. It is also active against Gram-negative organisms such as Escherichia coli and Haemophilus influenzae. Mupirocin Ointment is used for skin infections, e.g. impetigo, folliculitis, furunculosis.

Posology and method of administration

Posology

Adults (including elderly) and Paediatric population

Mupirocin Ointment should be applied to the affected area up to three times a day for up to 10 days.

The area may be covered with a dressing or occluded if desired.

Method of administration

Topical.

Do not mix with other preparations as there is a risk of dilution, resulting in a reduction of the antibacterial activity and potential loss of stability of the mupirocin in the ointment.

Overdose

Symptoms

There is currently limited experience with overdosage of mupirocin.

Management

The toxicity of mupirocin is very low. In the event of accidental ingestion of the ointment, symptomatic treatment should be given.

In case of erroneous oral intake of large quantities of the ointment, renal function should be closely monitored in patients with renal insufficiency because of the possible side effects of polyethylene glycol.

There is no specific treatment for an overdose of mupirocin. In the event of overdose, the patient should be treated supportively with appropriate monitoring as necessary. Further management should be as clinically indicated or as recommended by the national poisons centre, where available.

Shelf life

Shelf life: 2 years.

Once open use within six months.

Special precautions for storage

Do not store above 25°C.

Nature and contents of container

15g aluminium tube internally coated with an epoxy non-toxic resin closed with polyethylene screw caps.

Special precautions for disposal and other handling

No special requirements.

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