Source: FDA, National Drug Code (US) Revision Year: 2018
Sodium nitroprusside is disodium pentacyanonitrosylferrate(2-) dihydrate, a hypotensive agent whose structural formula is:
Sodium Nitroprusside has molecular formula Na2[Fe(CN)5NO] • 2H2O and molecular weight of 297.95. Dry sodium nitroprusside is a reddish-brown powder, soluble in water.
Sodium nitroprusside solution is rapidly degraded by trace contaminants, often with resulting color changes [see Dosage and Administration (2.1)].
NIPRIDE RTU is supplied as a sterile, unpreserved, colorless to red-brown solution packaged in a single-use 100-mL vial. Each 100 mL of solution in vial contains 50 mg of sodium nitroprusside (0.5 mg/mL), 900 mg of sodium chloride, USP (9 mg/mL), in sterile water for injection, USP.
NIPRIDE RTU is also supplied as a sterile, unpreserved, colorless to red-brown solution packaged in a single-use 100-mL vial. Each 100 mL of solution in vial contains 20 mg of sodium nitroprusside (0.2 mg/mL), 900 mg of sodium chloride, USP (9 mg/mL), in sterile water for injection, USP.
NIPRIDE RTU is also supplied as a sterile, unpreserved, colorless to red-brown solution packaged in a single-use 50-mL vial. Each 50 mL of solution in vial contains 10 mg of sodium nitroprusside (0.2 mg/mL), 450 mg of sodium chloride, USP (9 mg/mL), in sterile water for injection, USP.
| Dosage Forms and Strengths |
|---|
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Injection: 50 mg/100 mL of 0.9% sodium chloride (0.5 mg/mL), 20 mg/100 mL of 0.9% sodium chloride (0.2 mg/mL), and 10 mg/50 mL of 0.9% sodium chloride (0.2 mg/mL). NIPRIDE RTU is supplied as a sterile, unpreserved, colorless to red-brown solution available in a single-use vial. |
| How Supplied |
|---|
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NIPRIDE RTU is supplied in amber-colored, single-dose, 50 mg/100 mL (0.5 mg/mL) Fliptop Vials (NDC 51754-1006-1), 20 mg/100 mL (0.2 mg/mL) Fliptop Vials (NDC 51754-1029-1) and 10 mg/50 mL (0.2 mg/mL) Fliptop Vials (NDC 51754-1018-1). To protect NIPRIDE RTU from light, vial should be stored in its carton until used. |
| Drug | Countries | |
|---|---|---|
| NIPRIDE | Canada, United States |
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