Nitroprusside

Chemical formula: Câ‚…FeN₆O  Molecular mass: 215.938 g/mol  PubChem compound: 11963622

Active ingredient description

The principal pharmacological action of nitroprusside is relaxation of vascular smooth muscle and consequent dilation of peripheral arteries and veins. Other smooth muscle (e.g. uterus, duodenum) is not affected. Nitroprusside is more active on veins than on arteries.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C02DD01 Nitroprusside C Cardiovascular system → C02 Antihypertensives → C02D Arteriolar smooth muscle, agents acting on → C02DD Nitroferricyanide derivatives
Discover more medicines within C02DD01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NIPRIDE RTU Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR
DBL SODIUM NITROPRUSSIDE Solution for injection Medicines and Medical Devices Safety Authority (NZ) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 14402-89-2
DrugBank Drug: DB00325
KEGG Drug: D00614
PubChem Compound: 11963622
RxNorm Ingredient: 7476
SNOMED-CT Concept: 372860000
Nitroprusside (substance)
UNII Identifier: 169D1260KM
NITROPRUSSIDE
UNII Identifier: EAO03PE1TC
SODIUM NITROPRUSSIDE

Medicines

Nitroprusside is an active ingredient of these brands:

United States (US)

Austria (AT)

Canada (CA)

Estonia (EE)

Finland (FI)

Hong Kong (HK)

Israel (IL)

Japan (JP)

Lithuania (LT)

South Africa (ZA)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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