Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2015 Publisher: Church & Dwight UK Limited, Premier House, Shearway Business Park, Pent Road, Folkestone, Kent, CT19 4RJ, United Kingdom
Pharmacotherapeutic group: Local anaesthetics
ATC code: N01BA05
Benzocaine is a local anaesthetic of the ester type, acting to produce reversible loss of sensation by preventing or diminishing the generation and transmission of sensory nerve impulses near the site of application. Depolarisation of the neuronal membrane and ion exchange are reversibly inhibited.
Benzocaine is rapidly absorbed through mucous membranes and damaged skin.
Anaesthetics of the ester type are hydrolysed by esterases in the plasma and, to a lesser extent, in the liver.
There are no additional pre-clinical data of relevance to the prescriber.
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