ROVAMYCIN Film-coated tablet Ref.[8592] Active ingredients: Spiramycin

Publisher: Sanofi-aventis Israel ltd, P.O.B. 8090 Netanya 4250499

Product name and form

ROVAMYCIN.

Pharmaceutical Form

Film-coated tablet.

Qualitative and quantitative composition

Active ingredient: each tablet contains 1.5 MIU Spiramycin.

Excipients: Microcrystalline cellulose, Gelifiable maize starch, Hydroxypropylcellulose, Sodium croscarmellose, Hypromellose, Magnesium stearate, Macrogol 6000, Titanium dioxide, Anhydrous colloidal silica.

Active Ingredient Description
Spiramycin

Antibacterial antibiotic belonging to the macrolides family. Spiramycin inhibits translocation by binding to bacterial 50S ribosomal subunits with an apparent 1:1 stoichiometry. This antibiotic is a potent inhibitor of the binding to the ribosome of both donor and acceptor substrates. Spiramycin induces rapid breakdown of polyribosomes, an effect which has formerly been interpreted as occurring by normal ribosomal run-off followed by an antibiotic-induced block at or shortly after initiation of a new peptide.

List of Excipients

Pack sizes and marketing

Marketing authorization holder

Sanofi-aventis Israel ltd, P.O.B. 8090 Netanya 4250499

Drugs

Drug Countries
ROVAMYCIN Canada, Israel

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