VERAPAMIL Oral solution Ref.[7556] Active ingredients: Verapamil

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2022  Publisher: Essential Pharma Ltd, 7 Egham Business Village, Crabtree Road, Egham, Surrey, TW20 8RB, UK

Product name and form

Verapamil 40mg/5ml Oral Solution.

Pharmaceutical Form

Oral Solution.

Qualitative and quantitative composition

Verapamil Hydrochloride 40mg/5ml.

Excipients with known effect:

Propylene glycol (E1520): 500mg/5ml
Liquid Maltitol (E965): 2500mg/5ml
Ethanol: 2.1mg/5ml
Benzoic acid (E210): 5mg/5ml

For the full list of excipients, see Section 6.1.

Active Ingredient Description
Verapamil

Verapamil inhibits the transmembrane influx of calcium ions into the heart and vascular smooth muscle cell. The myocardial oxygen demand is lowered directly as a result of the effect on the energy consuming metabolic processes of the myocardial cell and indirectly due to a reduction of the afterload. Due to its effect on coronary vascular smooth muscle, verapamil enhances myocardial blood flow, even in postโ€stenotic areas, and relieves coronary spasms. These properties contribute to the antiโ€ischaemic and antianginal efficacy of verapamil in all types of coronary artery disease.

List of Excipients

Propylene glycol
Benzoic acid
Liquid maltitol
Dill water concentrate (contains ethanol)
Liquorice flavour
Citric acid monohydrate
Sodium citrate
Purified water

Pack sizes and marketing

Bottle: Amber (Type III) glass.

Closure: HDPE, EPE wadded, tamper evident, child resistant closure.

Pack Size: 150ml.

Marketing authorization holder

Essential Pharma Ltd, 7 Egham Business Village, Crabtree Road, Egham, Surrey, TW20 8RB, UK

Marketing authorization dates and numbers

PL 41871/0021

23 May 2001 / 23 Feb 2007

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