CO-TROX

This brand name is authorized in Nigeria.

Active ingredients

The drug CO-TROX contains a combination of these active pharmaceutical ingredients (APIs):

1	Sulfamethoxazole UNII JE42381TNV - SULFAMETHOXAZOLE
	Sulfamethoxazole competitively inhibits the utilisation of para-aminobenzoic acid in the synthesis of dihydrofolate by the bacterial cell resulting in bacteriostasis.
	Read more about Sulfamethoxazole
2	Trimethoprim UNII AN164J8Y0X - TRIMETHOPRIM
	Trimethoprim is a dihydrofolate reductase inhibitor, inhibiting the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid, required for the synthesis of some amino acids. Its effects are considerably greater on the cells of micro-organisms than on the mammalian cells.
	Read more about Trimethoprim

Packages

This drug has been approved in Nigeria as follows:

Identifier	Form	Presentation	Description	Approval
04-0061	Tablet	CO-TROX TABLET TAB 400 mg; 80 mg 10010,11000	CO-TROX TABLET TRIMETHOPRIM B.P. 80MG, SULPHAMETHOXAZOLE B.P. Trimethoprim B.P. 80mg, Sulphamethoxazole B.P. 400mg, Nipagin (Methyl Paraben), Nipasol (Propyl Paraben), Gum Acacia B.P., Corn Starch B.P. (Paste), Corn Starch B.P. (Bulk), Corn Starch B.P. (Lubricant), Talcum B.P., Magnesium Stearate, Purified Water 04-0061 Drugs ANTIINFECTIVES FOR SYSTEMIC USE Nigerian Products 10010,11000 Prescription Only Medicine (POM) 27/07/2023 VITABIOTICS NIGERIA LIMITED, MOBOLAJI JOHNSON AVENUE, OREGUN INDUSTRIAL ESTATE, IKEJA LAGOS LAGOS 8023770671 dayo.otiko@yahoo.com VITABIOTICS NIGERIA LIMITED, 35, MOBOLAJI JOHNSON AVENUE, OREGUN INDUSTRIAL ESTATE, IKEJA, LAGOS, NIGERIA., Nigeria	30/11/2023
04-9386	Suspension	CO-TROX® PAEDIATRIC SUSPENSION SUSP 200 mg/5 mL; 40mg/5 mL 50ML	CO-TROX® PAEDIATRIC SUSPENSION SULPHAMETHOXAZOLE B.P. 200MG, TRIMETHOPRIM B.P. 40MG/5ML Sulphamethoxazole B.P. 200mg, Trimethoprim B.P. 40mg, Nipagin (Methyl Paraben), Nipasol (Propyl Paraben), Sucrose B.P., Sodium C.M.C. U.S.P, Sodium Citrate U.S.P, Sunset Yellow, Tween 80, Propylene Glycol, Orange Flavour, Raspberry Flavour, Purified Water B.P. Apr-86 Drugs ANTIINFECTIVES FOR SYSTEMIC USE Nigerian Products 50ML POM 1 27/07/2023 VITABIOTICS NIGERIA LIMITED, MOBOLAJI JOHNSON AVENUE, OREGUN INDUSTRIAL ESTATE, IKEJA LAGOS LAGOS 8023770671 dayo.otiko@yahoo.com VITABIOTICS NIGERIA LIMITED, 35, MOBOLAJI JOHNSON AVENUE, OREGUN INDUSTRIAL ESTATE, IKEJA, LAGOS, NIGERIA., Nigeria	30/11/2023

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
J01EE01	Sulfamethoxazole and trimethoprim	J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01E Sulfonamides and trimethoprim → J01EE Combinations of sulfonamides and trimethoprim, incl. derivatives
Discover more medicines within J01EE01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
NG	Registered Drug Product Database	04-0061, 04-9386