COPTRINE

This brand name is authorized in Nigeria.

Active ingredients

The drug COPTRINE contains a combination of these active pharmaceutical ingredients (APIs):

1	Sulfamethoxazole UNII JE42381TNV - SULFAMETHOXAZOLE
	Sulfamethoxazole competitively inhibits the utilisation of para-aminobenzoic acid in the synthesis of dihydrofolate by the bacterial cell resulting in bacteriostasis.
	Read more about Sulfamethoxazole
2	Trimethoprim UNII AN164J8Y0X - TRIMETHOPRIM
	Trimethoprim is a dihydrofolate reductase inhibitor, inhibiting the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid, required for the synthesis of some amino acids. Its effects are considerably greater on the cells of micro-organisms than on the mammalian cells.
	Read more about Trimethoprim

Packages

This drug has been approved in Nigeria as follows:

Identifier	Form	Presentation	Description	Approval
04-7237	Suspension	COPTRINE SUSPENSION SUSP 200 mg/5 mL; 40mg/5 mL X 50ML	20 RNW-PP-310585 COPTRINE SUSPENSION TRIMETHOPRIM + SULPHAMETHOXAZOLE SULPHAMETHOXAZOLE 80.000KG, TRIMETHOPRIM MICRONIZED POWDER 16.000KG, SUCROSE 500.000KG, SODIUM SACCHARIN 2.000KG, METHYL PARABEN 3.335KG, SODIUM PROPYL PARABEN 1.871KG, PROPYLENE GLYCOL 39.604KG, SODIUM CARBOXYL METHYL CELLULOSE (MEDIUM VISCOSITY) 3.960KG, AEROSIL 200 5.941KG, XANTHAN GUM 6.321KG, SODIUM CITRATE 1.200KG, POLYSORBATE 80 (TWEEN 80) 6.000KG, BANANA FLAVOUR (LIQUID) 5.000KG, ETHANOL 96% 20.198L, ANISEED OIL 0.594KG, PURIFIED WATER TO VOLUME 2000.00L Apr-37 Drugs Nigerian Products X50ml POM 1 1/30/2023 DRUGFIELD PHARMACEUTICALS LIMITED., LYNSON CHEMICAL AVENUE, KM 38 LAGOS-ABEOKUTA EXPRESSWAY, SANGO-OTA,OGUN STATE 8029055002 info@drugfieldpharma.com DRUGFIELD PHARMACEUTICALS LIMITED, 48, AKEJU STREET, PALMGROVE, SOMOLU, LAGOS STATE. P.O BOX 5831, IKEJA, LAGOS STATE., Nigeria	28/09/2023
A11-100609	Tablet	COPTRINE DOUBLE STRENGTH TABLETS TAB 800 mg; 160 mg 1x10,500	94 NF-PP-255550 COPTRINE DOUBLE STRENGTH TABLETS SULPHAMETHOXAZOLE 800MG + TRIMETHOPRIM 160MG Sulphamethoxazole 4.00Kg, Trimethoprim 0.80Kg, Lactose Monohydrate (Mesh 200) 145.00g, Povidone K30 58.00g, Corn Starch 120.00g, Sodium Starch Glycolate 33.75g, Methyl Paraben 5.00g, Propyl Paraben 2.50g, Sodium Starch Glycolate 38.75g, Magnesium Stearate 37.00g, Aerosil 200 10.00g A11-100609 Drugs Nigerian Products 1x10,500 POM 1 3/4/2022 DRUGFIELD PHARMACEUTICALS LIMITED., LYNSON CHEMICAL AVENUE, KM 38 LAGOS-ABEOKUTA EXPRESSWAY, SANGO-OTA,OGUN STATE 8029055002 info@drugfieldpharma.com DRUGFIELD PHARMACEUTICALS LIMITED, 48, AKEJU STREET, PALMGROVE, SOMOLU, LAGOS STATE. P.O BOX 5831, IKEJA, LAGOS STATE., Nigeria	21/12/2023

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
J01EE01	Sulfamethoxazole and trimethoprim	J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01E Sulfonamides and trimethoprim → J01EE Combinations of sulfonamides and trimethoprim, incl. derivatives
Discover more medicines within J01EE01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
NG	Registered Drug Product Database	04-7237, 04-7720, A11-100609