ORFETRIM

This brand name is authorized in Nigeria.

Active ingredients

The drug ORFETRIM contains a combination of these active pharmaceutical ingredients (APIs):

1	Sulfamethoxazole UNII JE42381TNV - SULFAMETHOXAZOLE
	Sulfamethoxazole competitively inhibits the utilisation of para-aminobenzoic acid in the synthesis of dihydrofolate by the bacterial cell resulting in bacteriostasis.
	Read more about Sulfamethoxazole
2	Trimethoprim UNII AN164J8Y0X - TRIMETHOPRIM
	Trimethoprim is a dihydrofolate reductase inhibitor, inhibiting the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid, required for the synthesis of some amino acids. Its effects are considerably greater on the cells of micro-organisms than on the mammalian cells.
	Read more about Trimethoprim

Packages

This drug has been approved in Nigeria as follows:

Identifier	Form	Presentation	Description	Approval
A4-3540	Tablet	ORFETRIM TABLET TAB 400 mg; 80 mg 11000s,1010	91 RNW-PP-136582 ORFETRIM TABLET SULPHAMETHOXAZOLE + TRIMETHOPRIM SULPHAMETHOXAZOLE 400MG + TRIMETHOPRIM 80MG A4-3540 Drugs Nigerian Products 1000s,1010 POM 1 8/2/2022 ORFEMA PHARMACEUTICAL INDUSTRY LIMITED, 5, ATILADE ADEBOWALE STREET, OFF DADDY SAVAGE ROAD, OFF IJU ROAD 14537852 info@orfema.com ORFEMA PHARMACEUTICAL INDUSTRY LIMITED, 5, ATILADE ADEBOWALE STREET, FAGBA – IJU, LAGOS STATE. , Nigeria	21/12/2023

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
J01EE03	Sulfametrole and trimethoprim	J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01E Sulfonamides and trimethoprim → J01EE Combinations of sulfonamides and trimethoprim, incl. derivatives
Discover more medicines within J01EE03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
NG	Registered Drug Product Database	A4-3540