Afatinib

Chemical formula: C₂₄H₂₅ClFN₅O₃  Molecular mass: 485.938 g/mol  PubChem compound: 10184653

Therapeutic indications

Afatinib is indicated for:

Non-small cell lung cancer (NSCLC) with activating EGFR mutation

Population group: only adults (18 years old or older)

Afatinib as monotherapy is indicated for the treatment of epidermal Growth Factor Receptor (EGFR) TKI-naïve adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating EGFR mutation(s).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Non-small cell lung cancer (NSCLC) of squamous histology

Population group: only adults (18 years old or older)

Afatinib as monotherapy is indicated for the treatment of adult patients with locally advanced or metastatic NSCLC of squamous histology progressing on or after platinum-based chemotherapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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