Chemical formula: C₂₈H₃₇ClO₇ Molecular mass: 521.042 g/mol PubChem compound: 21700
Beclometasone is a pro-drug with weak glucocorticoid receptor binding affinity. It is extensively hydrolysed via esterase enzymes to the active metabolite beclometasone-17-monopropionate (B-17-MP), which has potent topical anti-inflammatory activity.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A07EA07 | Beclometasone | A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07E Intestinal antiinflammatory agents → A07EA Corticosteroids acting locally |
| D07AC15 | Beclometasone | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AC Corticosteroids, potent (group III) |
| R01AD01 | Beclometasone | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AD Corticosteroids |
| R03BA01 | Beclometasone | R Respiratory system → R03 Drugs for obstructive airway diseases → R03B Other drugs for obstructive airway diseases, inhalants → R03BA Glucocorticoids |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| QVAR MDI Pressurised inhalation, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| CLENIL Pressurised inhalation solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Beclometasone is an active ingredient of these brands:
United States (US)Albania (AL)
Australia (AU)Austria (AT)
Brazil (BR)
Croatia (HR)Cyprus (CY)Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)Italy (IT)
Lithuania (LT)Malta (MT)
Mexico (MX)Netherlands (NL)New Zealand (NZ)
Poland (PL)
Romania (RO)Singapore (SG)South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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