Chemical formula: C₁₇H₂₀N₂O₅S Molecular mass: 364.416 g/mol PubChem compound: 2471
Bumetanide is a potent loop diuretic with a rapid onset and a short duration of action. The primary site of action is the ascending limb of the loop of Henle where it exerts inhibiting effects on electrolyte reabsorption, causing its diuretic and natriuretic action.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03CA02 | Bumetanide | C Cardiovascular system → C03 Diuretics → C03C High-ceiling diuretics → C03CA Sulfonamides, plain |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| BURINEX Tablet | Health Products Regulatory Authority (IE) | MPI, EU: SmPC | |
| BUMETANIDE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Bumetanide is an active ingredient of these brands:
United States (US)Austria (AT)Brazil (BR)Canada (CA)Ecuador (EC)France (FR)Ireland (IE)Malta (MT)Mexico (MX)Netherlands (NL)New Zealand (NZ)Singapore (SG)South Africa (ZA)Spain (ES)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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