Clopidogrel

Chemical formula: C₁₆H₁₆ClNO₂S  Molecular mass: 321.822 g/mol  PubChem compound: 60606

Active ingredient description

Clopidogrel is a prodrug, one of whose metabolites is an inhibitor of platelet aggregation. Clopidogrel must be metabolised by CYP450 enzymes to produce the active metabolite that inhibits platelet aggregation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B01AC04 Clopidogrel B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AC Platelet aggregation inhibitors excl. heparin
Discover more medicines within B01AC04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CLOPIDOGREL ZENTIVA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
PLAVIX Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 113665-84-2
CAS Substance: 120202-66-6
DrugBank Drug: DB00758
KEGG Drug: D00769
PubChem Compound: 60606
RxNorm Ingredient: 32968
SNOMED-CT Concept: 386952008
Clopidogrel (substance)
UNII Identifier: A74586SNO7
CLOPIDOGREL

Medicines

Clopidogrel is an active ingredient of these brands:

United States (US)

  • PLAVIX as CLOPIDOGREL BISULFATE

Albania (AL)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

  • PLAVIX as CLOPIDOGREL BISULFATE

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

  • GREPID as CLOPIDOGREL BESYLATE
  • PLAVIX as CLOPIDOGREL BISULFATE

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Mexico (MX)

  • PLAVIX as CLOPIDOGREL BISULFATE
  • (combination) COPLAVIX as CLOPIDOGREL BISULFATE

Netherlands (NL)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

  • PLAVIX as CLOPIDOGREL BISULFATE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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