Chemical formula: C₁₈H₁₉ClN₄ Molecular mass: 326.823 g/mol PubChem compound: 2818
Clozapine has been shown to be an antipsychotic agent that is different from classic antipsychotics. Clozapine has potent anti-alpha-adrenergic, anticholinergic, antihistaminic, and arousal-reaction-inhibiting effects. It has also been shown to possess antiserotoninergic properties.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N05AH02 | Clozapine | N Nervous system → N05 Psycholeptics → N05A Antipsychotics → N05AH Diazepines, oxazepines and thiazepines |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CLOZARIL Tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| ZAPONEX Orodispersible tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Clozapine is an active ingredient of these brands:
Albania (AL)Canada (CA)Estonia (EE)France (FR)Germany (DE)Italy (IT)Japan (JP)Lithuania (LT)Mexico (MX)Romania (RO)Singapore (SG)Tunisia (TN)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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