Chemical formula: C₁₁H₂₈ClN₅O Molecular mass: 281.198 g/mol PubChem compound: 62816
No clinical data are available on the use of colestipol hydrochloride in pregnant women. Though animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonic/foetal development, parturition or postnatal development, caution should be exercised when prescribing to pregnant women.
The use of colestipol in pregnancy or by women of childbearing age requires that the potential benefits of treatment be weighed against the possible hazards to the mother and child.
The safety of colestipol hydrochloride has not been established in breast-feeding women. Caution should be exercised when prescribing to breast-feeding women.
There are no data on the effect of colestipol hydrochloride on fertility in humans. A study conducted in rats did not result in any differences in reproductive parameters that might imply reproductive effects attributable to colestipol hydrochloride.
No adverse effect has been reported.
Adverse events are described by system organ class and frequency (very common ≥1/10; common ≥1/100 to <1/10; uncommon ≥1/1,000 to <1/100; rare ≥1/10,000 to <1/1,000; very rare <1/10,000) in the table below:
Uncommon: Decreased appetite
Uncommon: Insomnia
Very common: Migraine, Sinus headache, Headache
Uncommon: Dizziness
Uncommon: Angina pectoris, Tachycardia
Uncommon: Dyspnoea
Very common: Constipation, Abdominal pain, Abdominal discomfort
Common: Haematochezia, Haemorrhoidal haemorrhage, Abdominal distention, Dyspepsia, Nausea, Vomiting, Diarrhoea, Flatulence, Eructation
Uncommon: Peptic ulcer and bleeding, Haemorrhoids, Impaction
Uncommon: Cholecystitis, Cholelithiasis
Common: Rash
Uncommon: Urticaria, Dermatitis
Common: Arthritis, Arthralgia, Back pain, Musculoskeletal pain, Pain in extremity
Common: Fatigue
Uncommon: Chest pain, Oedema peripheral, Asthenia
Uncommon: Alanine aminotransferase increased, Aspartate aminotransferase increased, Blood alkaline phosphatase increased
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