Cromoglicic acid Other names: Sodium cromoglicate Cromolyn sodium Cromoglycate Cromoglicate Cromolyn Cromoglycate sodium

Chemical formula: C₂₃H₁₆O₁₁  Molecular mass: 468.367 g/mol  PubChem compound: 2882

Active ingredient description

Sodium cromoglicate (Cromoglicic acid) inhibits the activation of many of the cell types involved in the development and progression of asthma. Thus, sodium cromoglicate inhibits the release of inflammatory mediators including cytokines from mast cells and reduces the chemotactic activity of eosinophils and neutrophils.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A07EB01 Cromoglicic acid A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07E Intestinal antiinflammatory agents → A07EB Antiallergic agents, excl. corticosteroids
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D11AH03 Cromoglicic acid D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AH Agents for dermatitis, excluding corticosteroids
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R01AC01 Cromoglicic acid R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AC Antiallergic agents, excl. corticosteroids
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R03BC01 Cromoglicic acid R Respiratory system → R03 Drugs for obstructive airway diseases → R03B Other drugs for obstructive airway diseases, inhalants → R03BC Antiallergic agents, excl. corticosteroids
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S01GX01 Cromoglicic acid S Sensory organs → S01 Ophthalmologicals → S01G Decongestants and antiallergics → S01GX Other antiallergics
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Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
INTAL CFC-FREE Pressurised inhalation, suspension Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ALLERGY RELIEF Eye drops, Solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
NALCROM Capsule Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 15826-37-6
CAS Substance: 16110-51-3
DrugBank Drug: DB01003
KEGG Drug: D07753
PubChem Compound: 2882
RxNorm Ingredient: 2921
SNOMED-CT Concept: 372672009
Cromoglicic acid (substance)
UNII Identifier: Y0TK0FS77W
CROMOLYN

Medicines

Cromoglicic acid is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Canada (CA)

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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