Danaparoid Other names: Danaparoid sodium

Therapeutic indications

Danaparoid is indicated for:

Prevention of deep vein thrombosis in general or orthopaedic surgery

Population group: only adults (18 years old or older)

Prevention of deep vein thrombosis and its possible consequences in patients undergoing general or orthopaedic surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Thrombo-embolic disorders in development or history of heparin-induced thrombocytopenia (HIT)

Population group: only adults (18 years old or older)

Treatment of thrombo-embolic disorders in patients who require urgent parenteral anti-coagulation because of the development or history of heparin-induced thrombocytopenia (HIT).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Danaparoid is contraindicated in the following cases:

Acute bacterial endocarditis

Acute bacterial endocarditis

Locoregional anaesthesia

Regional anesthesia

Severe haemorrhagic diathesis, haemophilia, idiopathic thrombocytopenic purpura

at least one of
Congenital thrombocytopenia
Hemophilia
Chronic idiopathic thrombocytopenic purpura

Haemorrhagic stroke in the acute phase

Cerebral hemorrhage

Uncontrollable active bleeding state

Bleeding

Severe uncontrolled hypertension

Hypertensive crisis

Active gastroduodenal ulcer

Peptic ulcer

Diabetic retinopathy

Diabetic retinopathy

Hypersensitivity to sulphite

Pseudoallergic reaction to sulfite

Heparin-induced antibody

at least one of
Platelet factor 4-heparin complex Ab
Heparin antibody

Severe renal insufficiency

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe hepatic insufficiency

Hepatic failure stage IV

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2016: DANAPAROID SODIUM Solution for injection
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