Dihydrocodeine Other names: Drocode Paracodeine Parzone

Chemical formula: C₁₈H₂₃NO₃  Molecular mass: 301.38 g/mol  PubChem compound: 5284543

Therapeutic indications

Dihydrocodeine is indicated for:

Severe pain in cancer and other chronic conditions

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

For the relief of severe pain in cancer and other chronic conditions.

Dihydrocodeine is indicated for the treatment of opioid-responsive, chronic severe pain of non-malignant origin, after other conservative methods of analgesia have been tried. It is indicated for use in accordance with the current guidelines on chronic pain management and where there is no psychological contraindication, medicine-seeking behaviour or history of medicine misuse.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Post-operative pain

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Postoperative pain

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Non-productive cough

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Dry cough

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Dihydrocodeine is contraindicated in the following cases:

Severe chronic obstructive lung disease

Severe chronic obstructive pulmonary disease

Severe cor pulmonale

Cor pulmonale

Severe bronchial asthma

Severe asthma

Severe respiratory depression with hypoxia

at least one of
Decreased respiratory function
Hypoxia

Monoamine oxidase inhibitors

Monoamine oxidase inhibitors (MAOIs)

Paralytic ileus

Paralytic ileus

Acute alcoholism

Alcohol intoxication

Opiate addiction

Opioid dependence

Mental clouding

Confusion

Elevated intracerebral pressure

at least one of
Raised intracranial pressure
Injury of head

Hypotension

Hypotension

Hypovolaemia

Hypovolemia

Asthma attack

Exacerbation of asthma

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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