Disopyramide

Chemical formula: C₂₁H₂₉N₃O  Molecular mass: 339.475 g/mol  PubChem compound: 3114

Active ingredient description

Disopyramide is a myocardial depressant and has anti-cholinergic effects. It decreases membrane responsiveness, prolongs the effective refractory period (ERP) and slows automaticity in cells with augmented automaticity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01BA03 Disopyramide C Cardiovascular system → C01 Cardiac therapy → C01B Antiarrhythmics, class I and III → C01BA Antiarrhythmics, class Ia
Discover more medicines within C01BA03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
RYTHMODAN Capsules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
Rythmodan 100mg Capsules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 3737-09-5
DrugBank Drug: DB00280
KEGG Drug: D00303
PubChem Compound: 3114
RxNorm Ingredient: 3541
SNOMED-CT Concept: 372844004
Disopyramide (substance)
UNII Identifier: GFO928U8MQ
DISOPYRAMIDE

Medicines

Disopyramide is an active ingredient of these brands:

United States (US)

  • NORPACE as DISOPYRAMIDE PHOSPHATE

Australia (AU)

Canada (CA)

France (FR)

Japan (JP)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

South Africa (ZA)

Spain (ES)

Turkey (TR)

  • NORPACE as DISOPYRAMIDE PHOSPHATE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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