Chemical formula: C₂₁H₂₉N₃O Molecular mass: 339.475 g/mol PubChem compound: 3114
Disopyramide interacts in the following cases:
Although disopyramide has undergone animal tests for teratogenicity without evidence of any effect on the developing foetus, its safety in human pregnancy has not been established. Disopyramide has been reported to stimulate contractions of the pregnant uterus. The drug should only be used during pregnancy if benefits clearly outweigh the possible risks to the mother and foetus.
Studies have shown that oral disopyramide is secreted in breast milk, although no adverse effects to the infant have been noted. However, clinical experience is limited and disopyramide should only be used in lactation if, in the clinician’s judgement, it is essential for the welfare of the patient. The infant should be closely supervised, particularly for anticholinergic effects and drug levels determined if necessary. Ideally, if the drug is considered essential, an alternative method of feeding should be used.
Some adverse reactions may impair the patients ability to concentrate and react, and hence the ability to drive or operate machinery.
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