Dorzolamide Other names: Dorzolamide hydrochloride

Chemical formula: C₁₀H₁₆N₂O₄S₃  Molecular mass: 324.44 g/mol  PubChem compound: 5284549

Active ingredient description

Dorzolamide is a potent inhibitor of human carbonic anhydrase II. Following topical ocular administration, dorzolamide reduces elevated intra-ocular pressure, whether or not associated with glaucoma.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
S01EC03 Dorzolamide S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EC Carbonic anhydrase inhibitors
Discover more medicines within S01EC03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
TRUSOPT Eye drops, solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 120279-96-1
DrugBank Drug: DB00869
KEGG Drug: D07871
PubChem Compound: 5284549
RxNorm Ingredient: 60207
SNOMED-CT Concept: 373447009
Dorzolamide (substance)
UNII Identifier: 9JDX055TW1
DORZOLAMIDE

Medicines

Dorzolamide is an active ingredient of these brands:

United States (US)

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE

Albania (AL)

Australia (AU)

Austria (AT)

  • DORLAZEPT as DORZOLAMIDE HYDROCHLORIDE
  • DORZO-VISION as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORZASTAD as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORZOCOMP-VISION as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUOKOPT as DORZOLAMIDE HYDROCHLORIDE

Brazil (BR)

  • DORZAL as DORZOLAMIDE HYDROCHLORIDE
  • OCUPRESS as DORZOLAMIDE HYDROCHLORIDE
  • TIMOSOPT as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORZAL MT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DRUSOLOL as DORZOLAMIDE HYDROCHLORIDE
  • (combination) GLALFITAL as DORZOLAMIDE HYDROCHLORIDE
  • (combination) PRESSALIV as DORZOLAMIDE HYDROCHLORIDE

Canada (CA)

  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE

Croatia (HR)

  • DORVIS as DORZOLAMIDE HYDROCHLORIDE
  • OFTIDOR as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE
  • VIZIDOR as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORVIS PLUS as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUOKOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) OFTIDORIX as DORZOLAMIDE HYDROCHLORIDE

Cyprus (CY)

  • DOROLAD as DORZOLAMIDE HYDROCHLORIDE
  • DORZON as DORZOLAMIDE HYDROCHLORIDE
  • OPTODROP as DORZOLAMIDE HYDROCHLORIDE
  • ZORMID as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DOTIZ as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUOKOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) OPTODROP-CO as DORZOLAMIDE HYDROCHLORIDE

Ecuador (EC)

Estonia (EE)

Finland (FI)

  • AIKUM as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUOKOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) GLAUKOSTAD as DORZOLAMIDE HYDROCHLORIDE

France (FR)

  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSIDIME as DORZOLAMIDE HYDROCHLORIDE
  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) COSTEC as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUALKOPT

Germany (DE)

Hong Kong (HK)

  • LAMISOPT as DORZOLAMIDE HYDROCHLORIDE
  • REZLOD as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORTIMO as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORZOPTIC T as DORZOLAMIDE HYDROCHLORIDE
  • (combination) MARDOZIA as DORZOLAMIDE HYDROCHLORIDE

Ireland (IE)

  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE

Israel (IL)

  • DORZATOL as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE

Italy (IT)

  • DORZOCLAR
  • DORZONORM as DORZOLAMIDE HYDROCHLORIDE
  • DORZOSTILL as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE
  • ZOLIOP as DORZOLAMIDE HYDROCHLORIDE

  • (combination) BETACLAR as DORZOLAMIDE HYDROCHLORIDE
  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORTOZ as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORZAMOX as DORZOLAMIDE HYDROCHLORIDE
  • (combination) TIDOCOMB as DORZOLAMIDE HYDROCHLORIDE
  • (combination) ZITODOR as DORZOLAMIDE HYDROCHLORIDE

Japan (JP)

  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORMOLOL as DORZOLAMIDE HYDROCHLORIDE

Lithuania (LT)

  • NODOFREE as DORZOLAMIDE HYDROCHLORIDE
  • NODOM as DORZOLAMIDE HYDROCHLORIDE
  • OFTIDOR as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE
  • VIZIDOR as DORZOLAMIDE HYDROCHLORIDE

  • (combination) AMIPTIC as DORZOLAMIDE HYDROCHLORIDE
  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) OFTIDORIX as DORZOLAMIDE HYDROCHLORIDE
  • (combination) TIDOMAT as DORZOLAMIDE HYDROCHLORIDE

Malta (MT)

  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE

Mexico (MX)

  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE

Netherlands (NL)

  • TRUSMONO as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUALKOPT

New Zealand (NZ)

  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) DORTIMOPT as DORZOLAMIDE HYDROCHLORIDE

Nigeria (NG)

  • (combination) DORZOPTOL as DORZOLAMIDE HYDROCHLORIDE
  • (combination) IOTIM-D as DORZOLAMIDE HYDROCHLORIDE
  • (combination) MIDOZOL as DORZOLAMIDE HYDROCHLORIDE
  • (combination) VITASOPT as DORZOLAMIDE HYDROCHLORIDE

Poland (PL)

  • DORZOMA MONO as DORZOLAMIDE HYDROCHLORIDE
  • DORZOSTILL as DORZOLAMIDE HYDROCHLORIDE
  • DROPZOL as DORZOLAMIDE HYDROCHLORIDE
  • NODOFREE as DORZOLAMIDE HYDROCHLORIDE
  • NODOM as DORZOLAMIDE HYDROCHLORIDE
  • OFTIDOR as DORZOLAMIDE HYDROCHLORIDE
  • ROZALIN as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE
  • VIZIDOR as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DROPZOL TIM as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUOKOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) NODOFREE COMBI as DORZOLAMIDE HYDROCHLORIDE
  • (combination) NODOM COMBI as DORZOLAMIDE HYDROCHLORIDE
  • (combination) OFTIDORIX as DORZOLAMIDE HYDROCHLORIDE
  • (combination) ROZACOM as DORZOLAMIDE HYDROCHLORIDE
  • (combination) VIZIDOR DUO as DORZOLAMIDE HYDROCHLORIDE

Romania (RO)

  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUOKOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) SIFIOPT as DORZOLAMIDE HYDROCHLORIDE

Singapore (SG)

  • LAMISOPT as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE
  • TRUVEX as DORZOLAMIDE HYDROCHLORIDE
  • ZOLICHEK as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) COVEX as DORZOLAMIDE HYDROCHLORIDE
  • (combination) LAMISOPT PLUS as DORZOLAMIDE HYDROCHLORIDE
  • (combination) ZOLICHEK-T as DORZOLAMIDE HYDROCHLORIDE

South Africa (ZA)

  • CIPLASOPT as DORZOLAMIDE HYDROCHLORIDE
  • GLAUCOPRESS as DORZOLAMIDE HYDROCHLORIDE
  • GLAUMIDE as DORZOLAMIDE HYDROCHLORIDE
  • GOZOPT as DORZOLAMIDE HYDROCHLORIDE
  • SOPTICO as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) CIPLASOPT CO as DORZOLAMIDE HYDROCHLORIDE
  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORΖΟTIΜ as DORZOLAMIDE HYDROCHLORIDE
  • (combination) GLAUMIDE-TD as DORZOLAMIDE HYDROCHLORIDE
  • (combination) GLAUOPT CO as DORZOLAMIDE HYDROCHLORIDE
  • (combination) GLAUSOL as DORZOLAMIDE HYDROCHLORIDE
  • (combination) GLAUTIDOR as DORZOLAMIDE HYDROCHLORIDE
  • (combination) OCUDOR CO as DORZOLAMIDE HYDROCHLORIDE
  • (combination) TIMDOPT

Spain (ES)

  • ARZOLAN as DORZOLAMIDE HYDROCHLORIDE
  • TRUSOPT as DORZOLAMIDE HYDROCHLORIDE

  • (combination) ARZOTIM as DORZOLAMIDE HYDROCHLORIDE
  • (combination) COSDUO as DORZOLAMIDE HYDROCHLORIDE
  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUOKOPT as DORZOLAMIDE HYDROCHLORIDE

Tunisia (TN)

  • ALZOR as DORZOLAMIDE HYDROCHLORIDE

  • (combination) COSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUALKOPT
  • (combination) OPTODROP-CO as DORZOLAMIDE HYDROCHLORIDE
  • (combination) TOMEC as DORZOLAMIDE HYDROCHLORIDE
  • (combination) ZOLOL as DORZOLAMIDE HYDROCHLORIDE

Turkey (TR)

  • DORZAMED as DORZOLAMIDE HYDROCHLORIDE
  • XOLADOR as DORZOLAMIDE HYDROCHLORIDE

  • (combination) ARUDOR as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORZASOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DORZOTIM as DORZOLAMIDE HYDROCHLORIDE
  • (combination) DUOSOPT as DORZOLAMIDE HYDROCHLORIDE
  • (combination) OFTOMIX as DORZOLAMIDE HYDROCHLORIDE
  • (combination) TOMEC as DORZOLAMIDE HYDROCHLORIDE
  • (combination) XOLATIM as DORZOLAMIDE HYDROCHLORIDE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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