Dorzolamide Other names: Dorzolamide hydrochloride

Chemical formula: C₁₀H₁₆N₂O₄S₃  Molecular mass: 324.44 g/mol  PubChem compound: 5284549

Therapeutic indications

Dorzolamide is indicated for:

Elevated intra-ocular pressure

Population group: only adults (18 years old or older)

Dorzolamide is indicated as monotherapy in patients unresponsive to beta-blockers or in whom beta-blockers are contraindicated, in the treatment of elevated intra-ocular pressure in:

  • ocular hypertension,
  • open-angle glaucoma,
  • pseudoexfoliative glaucoma.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Elevated intra-ocular pressure

Population group: only adults (18 years old or older)

Dorzolamide is indicated as adjunctive therapy to beta-blockers in the treatment of elevated intra-ocular pressure in:

  • ocular hypertension,
  • open-angle glaucoma,
  • pseudoexfoliative glaucoma.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Dorzolamide is contraindicated in the following cases:

Severe renal impairment, hyperchloraemic acidosis

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)
Metabolic acidosis, NAG, acidifying salts

Pregnancy

Pregnancy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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