Epoprostenol

Chemical formula: C₂₀H₃₂O₅ Molecular mass: 352.465 g/mol PubChem compound: 5280427

Therapeutic indications

Epoprostenol is indicated for:

Idiopathic or heritable pulmonary arterial hypertension (PAH)

Population group: only adults (18 years old or older)

Epoprostenol is indicated for the treatment of pulmonary arterial hypertension (PAH) (idiopathic or heritable PAH and PAH associated with connective tissue diseases) in patients with WHO Functional Class III–IV symptoms to improve exercise capacity.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

2-4 ng/kg/min

Renal Dialysis

Population group: only adults (18 years old or older)

Epoprostenol is indicated for use in haemodialysis in emergency situations when use of heparin carries a high risk of causing or exacerbating bleeding or when heparin is otherwise contraindicated.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

4 ng/kg/min

Contraindications

Epoprostenol is contraindicated in the following cases:

Pulmonary oedema

Pulmonary edema

Congestive heart failure arising from severe left ventricular dysfunction

Congestive heart failure due to left ventricular systolic dysfunction

Hypersensitivity to the epoprostenol

Epoprostenol allergy

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