Escitalopram

Chemical formula: C₂₀H₂₁FN₂O  Molecular mass: 324.392 g/mol  PubChem compound: 146570

Active ingredient description

Escitalopram is a selective inhibitor of serotonin (5-HT) re-uptake with high affinity for the primary binding site. It also binds to an allosteric site on the serotonin transporter, with a 1000 fold lower affinity. The inhibition of 5-HT re-uptake is the only likely mechanism of action explaining the pharmacological and clinical effects of escitalopram.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
N06AB10 Escitalopram N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AB Selective serotonin reuptake inhibitors
Discover more medicines within N06AB10

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 CIPRALEX Film-coated tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 LEXAPRO Tablet / Oral solution MPI, US: SPL/PLR FDA, National Drug Code (US)
 CIPRALEX Oral drops, solution MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 128196-01-0
DrugBank Drug: DB01175
PubChem Compound: 146570
RxNorm Ingredient: 321988
SNOMED-CT Concept: 400447003
Escitalopram (substance)
UNII Identifier: 4O4S742ANY
ESCITALOPRAM

Medicines

Escitalopram is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

  • CIPRALEX as ESCITALOPRAM OXALATE
  • ESTO as ESCITALOPRAM OXALATE

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

  • LEPAX as ESCITALOPRAM OXALATE
  • LEXAPRO as ESCITALOPRAM OXALATE

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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