Esketamine

Chemical formula: C₁₃H₁₆ClNO  Molecular mass: 237.73 g/mol  PubChem compound: 182137

Therapeutic indications

Esketamine is indicated for:

Major depressive disorder

Population group: only adults (18 - 65 years old)

Esketamine, in combination with a SSRI or SNRI, is indicated for adults with treatment-resistant Major Depressive Disorder, who have not responded to at least two different treatments with antidepressants in the current moderate to severe depressive episode.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Major depressive disorder

Population group: only elderly (65 years old or older)

Esketamine, in combination with a SSRI or SNRI, is indicated for adults with treatment-resistant Major Depressive Disorder, who have not responded to at least two different treatments with antidepressants in the current moderate to severe depressive episode.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Esketamine is contraindicated in the following cases:

Cardiovascular event, myocardial infarction (MI)

at least one of
Cardiovascular event
Myocardial infarction
Recent myocardial infarction

Intracerebral haemorrhage

Cerebral hemorrhage

Aneurysmal vascular disease

Aneurysm

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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