Chemical formula: C₆₃H₉₉FN₁₂O₂₅Si Molecular mass: 1,471.612 g/mol PubChem compound: 166177191
Flotufolastat (18F) is a radioactive diagnostic agent for intravenous use. Flotufolastat (18F) binds to PSMA (IC50 = 4.4 nM) expressed on cells, including prostate cancer cells, and is internalized. Prostate cancer cells usually overexpress PSMA. Fluorine-18 is a β+ emitting radionuclide that can be detected using positron emission tomography.
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| POSLUMA Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Flotufolastat ¹⁸F is an active ingredient of these brands:
United States (US)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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