Fluphenazine

Chemical formula: C₂₂H₂₆F₃N₃OS  Molecular mass: 437.522 g/mol  PubChem compound: 3372

Active ingredient description

Fluphenazine is an ester of the potent neuroleptic fluphenazine, a phenothiazine derivative of the piperazine type. The ester is slowly absorbed from the intramuscular site of injection and is then hydrolysed in the plasma to the active therapeutic agent, fluphenazine. It is used for the treatment and maintenance of schizophrenic patients and those with paranoid psychoses.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05AB02 Fluphenazine N Nervous system → N05 Psycholeptics → N05A Antipsychotics → N05AB Phenothiazines with piperazine structure
Discover more medicines within N05AB02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MODECATE Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 69-23-8
DrugBank Drug: DB00623
KEGG Drug: D07977
PubChem Compound: 3372
RxNorm Ingredient: 4496
SNOMED-CT Concept: 372730004
Fluphenazine (substance)
UNII Identifier: S79426A41Z
FLUPHENAZINE

Medicines

Fluphenazine is an active ingredient of these brands:

Brazil (BR)

Estonia (EE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

  • (combination) MOTIVAL as FLUPHENAZINE HYDROCHLORIDE

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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