Chemical formula: C₂₁H₄₃N₅O₇ Molecular mass: 1,390.728 g/mol PubChem compound: 3467
Gentamicin is usually bactericidal in action. Although the exact mechanism of action has not been fully elucidated, the drug appears to inhibit protein synthesis in susceptible bacteria by irreversibly binding to 30S ribosomal subunits.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D06AX07 | Gentamicin | D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06A Antibiotics for topical use → D06AX Other antibiotics for topical use |
| J01GB03 | Gentamicin | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01G Aminoglycoside antibacterials → J01GB Other aminoglycosides |
| S01AA11 | Gentamicin | S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AA Antibiotics |
| S02AA14 | Gentamicin | S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives |
| S03AA06 | Gentamicin | S Sensory organs → S03 Ophthalmological and otological preparations → S03A Antiinfectives → S03AA Antiinfectives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| GENTAMICIN Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| GENTAMICIN Eye / Ear drops | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Gentamicin is an active ingredient of these brands:
Australia (AU)Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Japan (JP)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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