Chemical formula: C₉H₂₃NO₇P₂ Molecular mass: 319.229 g/mol PubChem compound: 60852
Ibandronic acid belongs to the bisphosphonate group of compounds which act specifically on bone. Their selective action on bone tissue is based on the high affinity of bisphosphonates for bone mineral. Bisphosphonates act by inhibiting osteoclast activity, although the precise mechanism is still not clear. In vivo, ibandronic acid prevents experimentally-induced bone destruction caused by cessation of gonadal function, retinoids, tumours or tumour extracts.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M05BA06 | Ibandronic acid | M Musculo-skeletal system → M05 Drugs for treatment of bone diseases → M05B Drugs affecting bone structure and mineralization → M05BA Bisphosphonates |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| BONDRONAT Film-coated tablets | European Medicines Agency (EU) | MPI, EU: SmPC | |
| BONDRONAT Concentrate for solution for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
Ibandronic acid is an active ingredient of these brands:
United States (US)
Australia (AU)
Austria (AT)Brazil (BR)Croatia (HR)Ecuador (EC)
Estonia (EE)
Finland (FI)
Germany (DE)Hong Kong (HK)Ireland (IE)
Italy (IT)
Japan (JP)
Lithuania (LT)Mexico (MX)
Poland (PL)Spain (ES)Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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