Chemical formula: C₁₆H₁₆ClN₃O₃S Molecular mass: 365.835 g/mol PubChem compound: 3702
Indapamide is a sulfonamide derivative with an indole ring, pharmacologically related to thiazide diuretics, which acts by inhibiting the reabsorption of sodium in the cortical dilution segment. It increases the urinary excretion of sodium and chlorides and, to a lesser extent, the excretion of potassium and magnesium, thereby increasing urine output and having an antihypertensive action.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03BA11 | Indapamide | C Cardiovascular system → C03 Diuretics → C03B Low-ceiling diuretics, excl. thiazides → C03BA Sulfonamides, plain |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| NATRILIX Prolonged-release tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Indapamide is an active ingredient of these brands:
Albania (AL)Australia (AU)
Brazil (BR)
Canada (CA)
Croatia (HR)
Estonia (EE)
Finland (FI)
France (FR)Germany (DE)
Hong Kong (HK)Ireland (IE)
Israel (IL)Italy (IT)Lithuania (LT)
Malta (MT)
Mexico (MX)Netherlands (NL)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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