Chemical formula: C₃₃H₃₈N₄O₆ Molecular mass: 586.678 g/mol PubChem compound: 60838
Irinotecan is a semi-synthetic derivative of camptothecin. It is an antineoplastic agent which acts as a specific inhibitor of DNA topoisomerase I.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01CE02 | Irinotecan | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01C Plant alkaloids and other natural products → L01CE Topoisomerase 1 (TOP1) inhibitors |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CAMPTO Concentrate for solution for infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Irinotecan is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Ecuador (EC)
Finland (FI)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)
Japan (JP)Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Tunisia (TN)
Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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