The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
L | Antineoplastic and immunomodulating agents | |
2
|
L01 | Antineoplastic agents | |
3
|
L01C | Plant alkaloids and other natural products | |
4
|
L01CE | Topoisomerase 1 (TOP1) inhibitors |
| Code | Title | |
|---|---|---|
| L01CE01 | Topotecan | |
| L01CE02 | Irinotecan | |
| L01CE03 | ||
| L01CE04 |
| Active Ingredient |
|---|
|
Irinotecan is a semi-synthetic derivative of camptothecin. It is an antineoplastic agent which acts as a specific inhibitor of DNA topoisomerase I. |
|
Topotecan involves the inhibition of topoisomerase-I, an enzyme intimately involved in DNA replication. |
| Document | Type | Information Source | |
|---|---|---|---|
| CAMPTO Concentrate for solution for infusion | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| CAMPTOSAR Solution for injection | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| HYCAMTIN Hard capsule | MPI, EU: SmPC | European Medicines Agency (EU) | |
| HYCAMTIN Powder for concentrate for solution for infusion | MPI, EU: SmPC | European Medicines Agency (EU) |