Chemical formula: C₆H₈N₂O₈ Molecular mass: 236.136 g/mol PubChem compound: 6883
Isosorbide dinitrate is an organic nitrate, which in common with other cardioactive nitrates, is a vasodilator.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C01DA08 | Isosorbide dinitrate | C Cardiovascular system → C01 Cardiac therapy → C01D Vasodilators used in cardiac diseases → C01DA Organic nitrates |
| C05AE02 | Isosorbide dinitrate | C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AE Muscle relaxants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ISOKET RETARD Prolonged release tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ISOSORBIDE DINITRATE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ISOKET 1 mg/ml Concentrate for solution for injection / infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ISORDIL TITRADOSE Tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Isosorbide dinitrate is an active ingredient of these brands:
United States (US)
Albania (AL)Australia (AU)Ecuador (EC)Germany (DE)Hong Kong (HK)Ireland (IE)Lithuania (LT)Netherlands (NL)Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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