Ivacaftor and Lumacaftor is indicated for:
Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Lumacaftor/ivacaftor combination is are indicated for the treatment of cystic fibrosis (CF) in patients aged 1 year and older who are homozygous for the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Ivacaftor and Lumacaftor is contraindicated in the following cases:
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