Chemical formula: C₁₅H₁₃NO₃ Molecular mass: 255.269 g/mol PubChem compound: 3826
Ketorolac is a non-steroidal anti-inflammatory agent demonstrating analgesic and anti-inflammatory activity. Ketorolac inhibits the cyclo-oxygenase enzyme essential for biosynthesis of prostaglandins. Ketorolac has been shown to reduce prostaglandin levels in the aqueous humour after topical ophthalmic administration.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M01AB15 | Ketorolac | M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AB Acetic acid derivatives and related substances |
| S01BC05 | Ketorolac | S Sensory organs → S01 Ophthalmologicals → S01B Antiinflammatory agents → S01BC Antiinflammatory agents, non-steroids |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ACULAR Eye drops, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ACUVAIL Ophthalmic solution | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Ketorolac is an active ingredient of these brands:
United States (US)Austria (AT)
Brazil (BR)Canada (CA)Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Finland (FI)
France (FR)
Hong Kong (HK)Italy (IT)Lithuania (LT)Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)
Romania (RO)
Singapore (SG)South Africa (ZA)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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