Chemical formula: C₂₁H₁₉ClN₄O₄ Molecular mass: 426.86 g/mol PubChem compound: 9823820
Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that selectively inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4), in addition to other proangiogenic and oncogenic pathway-related RTKs including fibroblast growth factor (FGF) receptors FGFR1, 2, 3, and 4, the platelet derived growth factor (PDGF) receptor PDGFRα, KIT, and RET.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01EX08 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EX Other protein kinase inhibitors | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LENVIMA Hard capsule | European Medicines Agency (EU) | MPI, EU: SmPC |
Lenvatinib is an active ingredient of these brands:
United States (US)
Australia (AU)
Brazil (BR)
Canada (CA)
Cyprus (CY)
Ecuador (EC)France (FR)
Hong Kong (HK)
Israel (IL)
Japan (JP)
New Zealand (NZ)
Singapore (SG)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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