Lenvatinib

Chemical formula: C₂₁H₁₉ClN₄O₄  Molecular mass: 426.86 g/mol  PubChem compound: 9823820

Therapeutic indications

Lenvatinib is indicated for:

Differentiated thyroid carcinoma

Population group: only adults (18 years old or older)

Lenvatinib as monotherapy is indicated for the treatment of adult patients with progressive, locally advanced or metastatic, differentiated (papillary/follicular/Hürthle cell) thyroid carcinoma (DTC), refractory to radioactive iodine (RAI).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hepatocellular carcinoma

Population group: only adults (18 years old or older)

Lenvatinib as monotherapy is indicated for the treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have received no prior systemic therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Endometrial carcinoma

Population group: women, only adults (18 years old or older)

Lenvatinib in combination with pembrolizumab is indicated for the treatment of adult patients with advanced or recurrent endometrial carcinoma (EC) who have disease progression on or following prior treatment with a platinum-containing therapy in any setting and are not candidates for curative surgery or radiation.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Lenvatinib is contraindicated in the following cases:

Lactation

Lactation

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.