Levofloxacin

Chemical formula: C₁₈H₂₀FN₃O₄  Molecular mass: 361.368 g/mol  PubChem compound: 149096

Active ingredient description

Levofloxacin is a synthetic antibacterial agent of the fluoroquinolone class. As a fluoroquinolone antibacterial agent, levofloxacin acts on the DNA – DNA-gyrase complex and topoisomerase IV.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
J01MA12 Levofloxacin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01M Quinolone antibacterials → J01MA Fluoroquinolones
Discover more medicines within J01MA12
S01AE05 S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AE Fluoroquinolones
Discover more medicines within S01AE05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 LEVOFLOXACIN Solution for infusion MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 OFTAQUIX Eye drops, solution MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 QUINSAIR Nebuliser solution MPI, EU: SmPC European Medicines Agency (EU)
 LEVOFLOXACIN Film-coated tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 100986-85-4
CAS Substance: 138199-71-0
DrugBank Drug: DB01137
KEGG Drug: D08120
PubChem Compound: 149096
RxNorm Ingredient: 82122
SNOMED-CT Concept: 387552007
Levofloxacin (substance)
UNII Identifier: 6GNT3Y5LMF
LEVOFLOXACIN

Medicines

Levofloxacin is an active ingredient of these brands:

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

  • TAVANIC as Levofloxacin hemihydrate

Germany (DE)

  • TAVANIC as Levofloxacin hemihydrate

Hong Kong (HK)

Ireland (IE)

Israel (IL)

  • TAVANIC as Levofloxacin hemihydrate

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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