Lisinopril

Chemical formula: C₂₁H₃₁N₃O₅  Molecular mass: 405.488 g/mol  PubChem compound: 5362119

Therapeutic indications

Lisinopril is indicated for:

Hypertension

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Hypertension

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Heart failure

Population group: only adults (18 years old or older)

Treatment of symptomatic heart failure.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute myocardial infarction

Population group: only adults (18 years old or older)

Short-term (6 weeks) treatment of haemodynamically stable patients within 24 hours of an acute myocardial infarction.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Renal disease in hypertensive patients with type 2 diabetes mellitus

Population group: only adults (18 years old or older)

Treatment of renal disease in hypertensive patients with type 2 diabetes mellitus and incipient nephropathy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Lisinopril is contraindicated in the following cases:

Pregnancy

Pregnancy

Angioedema

at least one of
Angioedema
Angioedema caused by angiotensin-converting-enzyme inhibitor

Aliskiren in diabetes mellitus or renal impairment

Aliskiren and additionally at least one of
Diabetes mellitus



Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Sacubitril/valsartan

at least one of
Valsartan and sacubitril
Valsartan and additionally Sacubitril

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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