Chemical formula: C₉H₁₆ClN₃O₂ Molecular mass: 233.695 g/mol PubChem compound: 3950
Lomustine’s mode of action is believed to be partly as an alkylating agent and partly by inhibition of several steps in the synthesis of nucleic acid and inhibition of the repair of single strand breaks in DNA chains.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01AD02 | Lomustine | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AD Nitrosoureas |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LOMUSTINE MEDAC Capsule | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Lomustine is an active ingredient of these brands:
United States (US)Brazil (BR)Canada (CA)Netherlands (NL)New Zealand (NZ)Romania (RO)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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