Mefloquine

Chemical formula: C₁₇H₁₆F₆N₂O  Molecular mass: 378.312 g/mol  PubChem compound: 4046

Active ingredient description

Mefloquine acts on and destroys the asexual intraerythocytic forms of the human malaria parasites: Plasmodium falciparum, P. vivax. P. malariae and P. ovale. It is effective in the treatment and prophylaxis of malaria.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
P01BC02 Mefloquine P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01B Antimalarials → P01BC Methanolquinolines
Discover more medicines within P01BC02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LARIAM Tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 51773-92-3
CAS Substance: 53230-10-7
DrugBank Drug: DB00358
KEGG Drug: D04895
PubChem Compound: 4046
RxNorm Ingredient: 6694
SNOMED-CT Concept: 387505001
Mefloquine (substance)
UNII Identifier: TML814419R
MEFLOQUINE

Medicines

Mefloquine is an active ingredient of these brands:

Austria (AT)

  • LARIAM as MEFLOQUINE HYDROCHLORIDE

Cyprus (CY)

Estonia (EE)

  • LARIAM as MEFLOQUINE HYDROCHLORIDE

Finland (FI)

  • LARIAM as MEFLOQUINE HYDROCHLORIDE

France (FR)

  • LARIAM as MEFLOQUINE HYDROCHLORIDE

Hong Kong (HK)

Japan (JP)

Malta (MT)

Netherlands (NL)

  • LARIAM as MEFLOQUINE HYDROCHLORIDE

Singapore (SG)

South Africa (ZA)

  • LARIAM as MEFLOQUINE HYDROCHLORIDE
  • MEFLIAM as MEFLOQUINE HYDROCHLORIDE

United Kingdom (UK)

  • LARIAM as MEFLOQUINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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