Megestrol Other names: Megestrol acetate

Chemical formula: C₂₂H₃₀O₃  Molecular mass: 384.516 g/mol  PubChem compound: 11683

Active ingredient description

Megestrol possesses pharmacological properties similar to those of natural progesterone. Megestrol acetate is a potent progestogen that exerts significant anti-oestrogenic effects. It has no androgenic or oestrogenic properties.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G03AC05 Megestrol G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03A Hormonal contraceptives for systemic use → G03AC Progestogens
Discover more medicines within G03AC05
G03DB02 Megestrol G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03D Progestogens → G03DB Pregnadien derivatives
Discover more medicines within G03DB02
L02AB01 Megestrol L Antineoplastic and immunomodulating agents → L02 Endocrine therapy → L02A Hormones and related agents → L02AB Progestogens
Discover more medicines within L02AB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MEGACE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 3562-63-8
CAS Substance: 595-33-5
DrugBank Drug: DB00351
KEGG Drug: D00952
PubChem Compound: 11683
RxNorm Ingredient: 6703
SNOMED-CT Concept: 126091007
Megestrol (substance)
UNII Identifier: EA6LD1M70M
MEGESTROL

Medicines

Megestrol is an active ingredient of these brands:

Brazil (BR)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

France (FR)

Hong Kong (HK)

Ireland (IE)

Italy (IT)

Lithuania (LT)

Poland (PL)

Romania (RO)

Singapore (SG)

Spain (ES)

Tunisia (TN)

Turkey (TR)

  • BOREA as MEGESTROL ACETATE
  • MEGACE as MEGESTROL ACETATE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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